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Advance Arginine is an amino acid that plays an important role in several important pathways, including the synthesis of proteins, the production of creatine phosphate, needed to produce ATP, and the synthesis of nitric oxide, a secondary messenger involved in blood flow.Arginine has gotten lots of attention lately for its potential heart benefits. l-arginine powder has an extremely bitter and unpleasant taste, which is difficult to mask. To make it taste better, you need to neutralize the alkalinity of the l-arginine with an acid, such as lemon juice.